Synthesis of 2-substituted 2H-chromenes using potassium vinyltrifluoroborates
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چکیده
منابع مشابه
Catalytic Synthesis of 2H‐Chromenes
2H-Chromenes (2H-1-benzopyran derivatives) display a broad spectrum of biological activities. The 2H-chromene substructure is an important structural motif present in a variety of medicines, natural products, and materials showing unique photophysical properties. Hence, the structural importance of the benzopyran moiety has elicited a great deal of interest in the field of organic synthesis and...
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متن کاملIron(II)-catalyzed trifluoromethylation of potassium vinyltrifluoroborates.
An iron(II)-catalyzed trifluoromethylation of potassium vinyltrifluoroborates has been developed. The reactions proceed under mild conditions and provide E/Z selectivities of > 95:5 for 2-aryl and -heteroarylvinyl substrates. Experimental observations suggest that the reaction does not proceed through a transmetallation of the RBF3K to the iron catalyst.
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ژورنال
عنوان ژورنال: Tetrahedron Letters
سال: 2008
ISSN: 0040-4039
DOI: 10.1016/j.tetlet.2008.01.008